Catalog: YT0934
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
CKR-2
Host Species
Rabbit
Reactivity
Mouse, Rat
Applications
WB, IF, ELISA
MW
46kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CKR-2 Polyclonal Antibody detects endogenous levels of CKR-2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
46kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from CKR-2 . at AA range: 250-330
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Specificity:
CKR-2 Polyclonal Antibody detects endogenous levels of CKR-2 protein.
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Gene Name:
CCR2
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Protein Name:
C-C chemokine receptor type 2
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Other Name:
CCR2 ;
CMKBR2 ;
C-C chemokine receptor type 2 ;
C-C CKR-2 ;
CC-CKR-2 ;
CCR-2 ;
CCR2 ;
Monocyte chemoattractant protein 1 receptor ;
MCP-1-R ;
CD antigen CD192
CMKBR2 ;
C-C chemokine receptor type 2 ;
C-C CKR-2 ;
CC-CKR-2 ;
CCR-2 ;
CCR2 ;
Monocyte chemoattractant protein 1 receptor ;
MCP-1-R ;
CD antigen CD192
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Background:
CCR2 (C-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CCR2 include idiopathic anterior uveitis and cd3zeta deficiency. Among its related pathways are Signaling by GPCR and A-beta Pathways: uptake and Degradation. GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR9. eceptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection. hemokine CC receptors (CCRs) predominantly recognize CC chemokines. CC chemokines are distinguished by having four conserved cysteines, with the first two cysteines being adjacent to each other. There are 10 chemokine CC receptors.
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Signaling Pathway
Organismal Systems >> Immune system >> Chemokine signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Reference Citation({{totalcount}})
Catalog: YT0934
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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