Catalog: YT0319
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
ARHGAP23
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, WB, ELISA
MW
162kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
ARHGAP23 Polyclonal Antibody detects endogenous levels of ARHGAP23 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
162kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from ARHGAP23 . at AA range: 470-550
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Specificity:
ARHGAP23 Polyclonal Antibody detects endogenous levels of ARHGAP23 protein.
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Gene Name:
ARHGAP23
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Protein Name:
Rho GTPase-activating protein 23
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Other Name:
ARHGAP23 ;
KIAA1501 ;
Rho GTPase-activating protein 23 ;
Rho-type GTPase-activating protein 23
KIAA1501 ;
Rho GTPase-activating protein 23 ;
Rho-type GTPase-activating protein 23
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Background:
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008],
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Function:
Function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor.,
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Cellular Localization:
cytosol,extracellular exosome,
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Tissue Expression:
Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor.
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Reference Citation({{totalcount}})
Catalog: YT0319
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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