The antiserum was produced against synthesized peptide derived from human SLC25A6. AA range:121-170

ANT3 Polyclonal Antibody detects endogenous levels of ANT3 protein.

SLC25A6

ADP/ATP translocase 3

SLC25A6 ;
ANT3 ;
CDABP0051 ;
ADP/ATP translocase 3 ;
ADP ;
ATP carrier protein 3 ;
ADP,ATP carrier protein, isoform T2 ;
ANT 2 ;
Adenine nucleotide translocator 3 ;
ANT 3 ;
Solute carrier family 25 member 6

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013],

Function:Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,miscellaneous:The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,subunit:Homodimer. Interacts with influenza A virus PB1-F2 protein and HIV-1 Vpr.,

Mitochondrion inner membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . The complex formed with ARL2BP, ARL2 and SLC25A6/ANT3 is expressed in mitochondria (By similarity). May localize to non-mitochondrial membranes (By similarity). .

>>Calcium signaling pathway ;
>>cGMP-PKG signaling pathway ;
>>Necroptosis ;
>>Cellular senescence ;
>>Neutrophil extracellular trap formation ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Huntington disease ;
>>Spinocerebellar ataxia ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Influenza A ;
>>Human T-cell leukemia virus 1 infection ;
>>Chemical carcinogenesis - reactive oxygen species ;
>>Diabetic cardiomyopathy