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Catalog: YT0158
Size
Price
Status
Qty.
200μL
$450.00
In stock

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100μL
$280.00
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40μL
$150.00
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Main Information
Target

AK6

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

20kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
AK6 Polyclonal Antibody detects endogenous levels of AK6 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
20kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human KAD6. AA range:11-60
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Specificity:
AK6 Polyclonal Antibody detects endogenous levels of AK6 protein.
show all
Protein Name:
Adenylate kinase isoenzyme 6
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Other Name:
TAF9 ;
AK6 ;
CINAP ;
AD-004 ;
CGI-137 ;
Adenylate kinase isoenzyme 6 ;
ATP-AMP transphosphorylase 6 ;
Coilin-interacting nuclear ATPase protein ;
hCINAP
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Database Link:
Organism Gene ID SwissProt
Human 6880; Q9Y3D8;
Mouse 108143; Q8VCP8;
Rat 373541; Q5EB68;
Background:
adenylate kinase 6(AK6) Homo sapiens This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
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Function:
regulation of cell growth, chromatin organization, transcription, transcription, DNA-dependent, transcription initiation,RNA elongation, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter,RNA elongation from RNA polymerase II promoter, protein complex assembly, protein amino acid acetylation,regulation of cell size, positive regulation of biosynthetic process, regulation of catabolic process, negative regulation of catabolic process, response to organic substance, regulation of specific transcription from RNA polymerase II promoter, positive regulation of specific transcription from RNA polymerase II promoter, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression, regulation of cell death, chromatin modification, covalent chromatin modification, histone modification, histone acetylation, regulation of proteolysis,positive regulation of cell growth, positive regulation of cellular biosynthetic process, regulation of cellular catabolic process, negative regulation of cellular catabolic process, regulation of cellular protein metabolic process, negative regulation of cellular protein metabolic process, regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of cellular component size, regulation of gene-specific transcription, RNA biosynthetic process, response to cytokine stimulus,cellular response to DNA damage stimulus, regulation of growth, regulation of protein catabolic process, negative regulation of protein catabolic process, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, positive regulation of gene-specific transcription, protein amino acid acylation, macromolecular complex subunit organization, histone H3 acetylation,regulation of transcription, positive regulation of cell size, negative regulation of proteolysis, positive regulation of transcription, DNA-dependent, positive regulation of growth, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, positive regulation of response to stimulus, positive regulation of nitrogen compound metabolic process, negative regulation of protein metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process, chromosome organization, negative regulation of cell death, regulation of response to cytokine stimulus, positive regulation of response to cytokine stimulus, macromolecular complex assembly, protein complex biogenesis, response to interleukin-1,
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Cellular Localization:
Nucleus, nucleoplasm. Nucleus, Cajal body. Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
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Tissue Expression:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.
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Research Areas:
>>Purine metabolism ;
>>Metabolic pathways ;
>>Nucleotide metabolism ;
>>Biosynthesis of cofactors ;
>>Ribosome biogenesis in eukaryotes
show all
Catalog: YT0158
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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