Catalog: YP1785
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
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Main Information
Target
MKP-7
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
73kD (Calculated)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of MKP-7 (Phospho-Ser446) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QFsPV
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
73kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
Antigen&Target Information
Immunogen:
Synthesized peptide derived from human MKP-7 (Phospho-Ser446)
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Specificity:
This antibody detects endogenous levels of MKP-7 (Phospho-Ser446) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QFsPV
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Gene Name:
DUSP16 KIAA1700 MKP7
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Protein Name:
MKP-7 (Phospho-Ser446)
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Other Name:
Dual specificity protein phosphatase 16 ;
EC 3.1.3.48 ;
Mitogen-activated protein kinase phosphatase 7 ;
MAP kinase phosphatase 7 ;
MKP-7 ;
EC 3.1.3.48 ;
Mitogen-activated protein kinase phosphatase 7 ;
MAP kinase phosphatase 7 ;
MKP-7 ;
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Background:
dual specificity phosphatase 16(DUSP16) Homo sapiens This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010],
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Function:
Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,Catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,Function:Involved in the inactivation of MAP kinases.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
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Cellular Localization:
Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
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Tissue Expression:
Bone marrow,Brain,Duodenum,PCR rescued clones,
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Research Areas:
>>MAPK signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YP1785
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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