Catalog: YP1209
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Collected
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Conjugated antibody
Main Information
Target
Vimentin
Host Species
Rabbit
Reactivity
Human:Y38, Mouse:Y38, Rat:Y38
Applications
WB, ELISA
MW
51kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-10000; ELISA 1:10000
Formulation
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
This antibody detects endogenous levels of Vimentin at Human:Y38;Mouse:Y38;Rat:Y38, It doesn't reacte with total protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTySL
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
51kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
Related Products
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Vimentin Rabbit pAb
YT4880
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YP1209
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Vimentin (Phospho Ser56) Rabbit pAb
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Primary Antibodies
Vimentin (Phospho Ser83) Rabbit pAb
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Primary Antibodies
Vimentin (Phospho Tyr61) Rabbit pAb
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ELISA Kits
Total VIM Cell-Based Colorimetric ELISA Kit
KA3428C
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ELISA Kits
Vimentin (Phospho Ser56) Cell-Based Colorimetric ELISA Kit
KA1539C
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ELISA Kits
Vimentin (Phospho Ser83) Cell-Based Colorimetric ELISA Kit
KA1538C
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Antigen&Target Information
Immunogen:
Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)
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Specificity:
This antibody detects endogenous levels of Vimentin at Human:Y38;Mouse:Y38;Rat:Y38, It doesn't reacte with total protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTySL
show all
Gene Name:
VIM
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Protein Name:
vimentin
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Other Name:
VIM
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Database Link:
Background:
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],
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Function:
Function:Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.,online information:Vimentin entry,PTM:One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.,sequence Caution:Intron retention.,similarity:Belongs to the intermediate filament family.,subunit:Homopolymer. Interacts with HCV core protein. Interacts with LGSN and SYNM.,tissue specificity:Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.,
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Cellular Localization:
Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .
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Tissue Expression:
Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
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Research Areas:
>>Epstein-Barr virus infection ;
>>MicroRNAs in cancer
>>MicroRNAs in cancer
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YP1209
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
Conjugated antibody
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