Catalog: YN8257
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
SH3RF2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
80kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of SH3RF2 at Human, Mouse,Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
80kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human SH3RF2
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Specificity:
This antibody detects endogenous levels of SH3RF2 at Human, Mouse,Rat
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Gene Name:
SH3RF2 PPP1R39 RNF158
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Protein Name:
Putative E3 ubiquitin-protein ligase SH3RF2 (Heart protein phosphatase 1-binding protein) (HEPP1) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (SH3 domain-containing RING finger protein 2)
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Database Link:
Function:
Has E3 ubiquitin-protein ligase activity . Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation . Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation . Inhibits PPP1CA phosphatase activity .
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Cellular Localization:
Nucleus .
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Reference Citation({{totalcount}})
Catalog: YN8257
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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