Catalog: YN8212
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
CERK
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
59kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of CERK at Human, Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
59kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CERK
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Specificity:
This antibody detects endogenous levels of CERK at Human, Mouse
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Gene Name:
CERK KIAA1646
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Protein Name:
Ceramide kinase (hCERK) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)
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Function:
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate . Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines . Shows a greater preference for D-erythro isomer of ceramides . Binds phosphoinositides .
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Cellular Localization:
Cytoplasm . Cell membrane ; Peripheral membrane protein .
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Tissue Expression:
High level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung.
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Reference Citation({{totalcount}})
Catalog: YN8212
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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