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Plexin B2 Rabbit pAb

-YN6730

Catalog: YN6730
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$160.00
In stock

0

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Main Information
Target

PLXNB2

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB

MW

202kD (Calculated)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Plexin B2 at Human, Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
202kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Plexin B2
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Specificity:
This antibody detects endogenous levels of Plexin B2 at Human, Mouse
show all
Gene Name:
PLXNB2 KIAA0315
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Protein Name:
Plexin-B2 (MM1)
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Database Link:
Organism Gene ID SwissProt
Human 23654; O15031;
Mouse 140570; B2RXS4;
Function:
Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling (By similarity). Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development (By similarity). Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248' (By similarity). Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development (By similarity). Regulates the migration of cerebellar granule cells in the developing brain (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton . Plays a role in axon guidance, invasive growth and cell migration . May modulate the activity of RAC1 and CDC42 (By similarity).
show all
Cellular Localization:
Cell membrane ; Single-pass type I membrane protein .
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Catalog: YN6730
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$160.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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