Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).
show all
Cellular Localization:
Cytoplasm.
show all
Tissue Expression:
Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue.