Catalog: YN6005
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
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Collected
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Main Information
Target
ENTR1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
48kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of SDCCAG3 at Human, Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
48kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human SDCCAG3
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Specificity:
This antibody detects endogenous levels of SDCCAG3 at Human, Mouse
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Gene Name:
SDCCAG3
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Protein Name:
Serologically defined colon cancer antigen 3 (Antigen NY-CO-3)
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Function:
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis . Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 . Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 . Plays a role in the formation of cilia . Involved in cargo protein localization, such as PKD2, at primary cilia . Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis (By similarity).
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Cellular Localization:
Cytoplasm . Early endosome . Endosome . Recycling endosome . Midbody . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Colocalizes in a WASHC2-dependent manner with the retromer CSC complex at endosomes (PubMed:25278552). During cytokinesis colocalized with PTPN13 at the midbody (PubMed:23108400). Colocalizes with IFT88 and gamma-tubulin at the basal body of primary cilia (PubMed:27767179). Colocalizes with IFT88 and pericentrin at the centrosome (PubMed:27767179). .
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Tissue Expression:
Expressed in the colon (at protein level).
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Reference Citation({{totalcount}})
Catalog: YN6005
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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