Catalog: YN5731
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
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Main Information
Target
CBS
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
61kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of CBS at Human, Mouse,Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
61kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
RRID
AB_3678962
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CBS
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Specificity:
This antibody detects endogenous levels of CBS at Human, Mouse,Rat
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Gene Name:
CBS
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Protein Name:
Cystathionine beta-synthase (Beta-thionase) (Serine sulfhydrase)
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Database Link:
Function:
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine . Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
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Cellular Localization:
Cytoplasm . Nucleus .
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Tissue Expression:
In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.
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Reference Citation({{totalcount}})
Catalog: YN5731
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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