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L-type Ca++ CP γ4 Rabbit pAb

-YN5521

Catalog: YN5521
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$160.00
In stock

0

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Collected

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Main Information
Target

L-type Ca++ CP γ4

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF

MW

35kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; IHC 1:200-500; IF 1:50-200
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
The antibody detects endogenous L-type Ca++ CP γ4 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Observed)
35kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthetic Peptide of L-type Ca++ CP γ4 AA range: 120-200
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Specificity:
The antibody detects endogenous L-type Ca++ CP γ4 protein.
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Gene Name:
CACNG4
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Protein Name:
Voltage-dependent calcium channel gamma-4 subunit
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Other Name:
CACNG4 ;
Voltage-dependent calcium channel gamma-4 subunit ;
Neuronal voltage-gated calcium channel gamma-4 subunit ;
Transmembrane AMPAR regulatory protein gamma-4 ;
TARP gamma-4
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Database Link:
Organism Gene ID SwissProt
Human 27092; Q9UBN1;
Mouse Q9JJV4;
Rat Q8VHW9;
Background:
calcium voltage-gated channel auxiliary subunit gamma 4(CACNG4) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],
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Function:
Function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein .
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Tissue Expression:
Detected in heart left ventricle.
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Research Areas:
>>MAPK signaling pathway ;
>>Cardiac muscle contraction ;
>>Adrenergic signaling in cardiomyocytes ;
>>Oxytocin signaling pathway ;
>>Hypertrophic cardiomyopathy ;
>>Arrhythmogenic right ventricular cardiomyopathy ;
>>Dilated cardiomyopathy
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Catalog: YN5521
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$160.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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