Catalog: YN5231
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
GRP4
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
74kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of human GRP4
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
74kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human GRP4 AA range: 487-537
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Specificity:
This antibody detects endogenous levels of human GRP4
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Gene Name:
RASGRP4
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Protein Name:
RAS guanyl-releasing protein 4
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Database Link:
Cellular Localization:
Cytoplasm. Cell membrane. Recruited to membranes upon activation by DAG.
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Tissue Expression:
Expressed by mast cells and their progenitors (at protein level). Specifically expressed in mononuclear leukocytes. Highly expressed in myeloid cells compared to lymphoid cells. Also detected in heart, skeletal muscle, spleen, liver, placenta and lung. Not detected in brain. Isoform 1 is the major isoform in normal individuals. Isoform 2 is more significantly expressed in a patient with asthma. Isoform 3 is more significantly expressed in a patient with asthma and a mastocytosis patient.
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Research Areas:
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Pathways in cancer
>>Ras signaling pathway ;
>>Pathways in cancer
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN5231
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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