Catalog: YN3936
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
TTL
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
41kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of TTL at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
41kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human TTL AA range: 160-210
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Specificity:
This antibody detects endogenous levels of TTL at Human/Mouse/Rat
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Gene Name:
TTL
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Protein Name:
TTL
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Database Link:
Background:
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008],
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Function:
Catalytic activity:ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.,cofactor:Magnesium.,cofactor:Potassium.,Function:Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.,similarity:Belongs to the tubulin--tyrosine ligase family.,similarity:Contains 1 TTL domain.,subunit:Monomer.,
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Reference Citation({{totalcount}})
Catalog: YN3936
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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