Catalog: YN3395
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
YMEL1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
85kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of YMEL1 at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
85kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human YMEL1 AA range: 136-186
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Specificity:
This antibody detects endogenous levels of YMEL1 at Human/Mouse/Rat
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Gene Name:
YME1L1 FTSH1 YME1L UNQ1868/PRO4304
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Protein Name:
YMEL1
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Other Name:
ATP-dependent zinc metalloprotease YME1L1 ;
ATP-dependent metalloprotease FtsH1 ;
Meg-4 ;
Presenilin-associated metalloprotease ;
PAMP ;
YME1-like protein 1 ;
ATP-dependent metalloprotease FtsH1 ;
Meg-4 ;
Presenilin-associated metalloprotease ;
PAMP ;
YME1-like protein 1 ;
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Background:
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
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Function:
cofactor:Binds 1 zinc ion per subunit .,Function:Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,
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Cellular Localization:
Mitochondrion inner membrane . Mitochondrion .
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YN3395
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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