Synthesized peptide derived from human S13A5 AA range: 313-363

This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat

SLC13A5 NACT

S13A5

Solute carrier family 13 member 5 ;
Na ;
+ ;
/citrate cotransporter ;
NaCT ;
Sodium-coupled citrate transporter ;
Sodium-dependent citrate transporter ;

This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],

Function:High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.,similarity:Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.,tissue specificity:Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.,

Cell membrane ; Multi-pass membrane protein .