Catalog: YN2338
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
LPIN2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
98kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
LPIN2 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
98kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 220-300
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Specificity:
LPIN2 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
LPIN2 KIAA0249
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Protein Name:
Phosphatidate phosphatase LPIN2 (Lipin-2)
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Background:
Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008],
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Function:
Disease:Defects in LPIN2 are the cause of Majeed syndrome [MIM:609628]. Majeed syndrome is an autosomal recessive disorder combining features of chronic recurrent multifocal osteomyelitis [MIM:259680], congenital dyserythropoietic anemia and inflammatory dermatosis.,online information:Repertory of FMF and hereditary autoinflammatory disorders mutations,similarity:Belongs to the lipin family.,tissue specificity:Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon.,
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Cellular Localization:
Nucleus . Cytoplasm, cytosol . Endoplasmic reticulum membrane . Translocates to endoplasmic reticulum membrane with increasing levels of oleate. .
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Tissue Expression:
Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon.
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Research Areas:
>>Glycerolipid metabolism ;
>>Glycerophospholipid metabolism ;
>>Metabolic pathways ;
>>mTOR signaling pathway ;
>>Alcoholic liver disease
>>Glycerophospholipid metabolism ;
>>Metabolic pathways ;
>>mTOR signaling pathway ;
>>Alcoholic liver disease
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN2338
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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