Catalog: YN1998
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
MDGA1
Host Species
Rabbit
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
MW
105kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
MDGA1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
105kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
MDGA1 Polyclonal Antibody detects endogenous levels of protein.
show all
Gene Name:
MDGA1 MAMDC3
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Protein Name:
MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)
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Background:
This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016],
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Function:
Function:Required for radial migration of cortical neurons in the superficial layer of the neocortex.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 MAM domain.,similarity:Contains 6 Ig-like (immunoglobulin-like) domains.,subcellular location:Associated with lipid rafts.,subunit:Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like domains with proteins in differentiating muscle.,tissue specificity:Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues.,
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Cellular Localization:
Cell membrane ; Lipid-anchor, GPI-anchor . Associated with lipid rafts.
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Tissue Expression:
Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues.
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Reference Citation({{totalcount}})
Catalog: YN1998
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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