Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
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Function:
Function:Inhibits SNARE complex formation by absorbing free syntaxin-1.,similarity:Belongs to the rad21 family.,subunit:Binds to syntaxin-1.,tissue specificity:Brain specific. Found in synapses.,
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Cellular Localization:
Membrane ; Single-pass membrane protein . Cell junction, synapse, synaptosome.