Catalog: YN0915
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
NNTM
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
119kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
NNTM Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
119kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 240-320
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Specificity:
NNTM Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
NNT
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Protein Name:
NAD(P) transhydrogenase, mitochondrial (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)
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Background:
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016],
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Function:
Catalytic activity:NADPH + NAD(+) = NADP(+) + NADH.,Function:The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.,similarity:In the C-terminal section; belongs to the PNT beta subunit family.,similarity:In the N-terminal section; belongs to the AlaDH/PNT family.,subunit:Homodimer.,
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Cellular Localization:
Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side .
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Tissue Expression:
Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues.
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Research Areas:
>>Nicotinate and nicotinamide metabolism ;
>>Metabolic pathways
>>Metabolic pathways
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Reference Citation({{totalcount}})
Catalog: YN0915
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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