Catalog: YN0629
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
DC1I2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
70kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
DC1I2 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
70kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
DC1I2 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
DYNC1I2 DNCI2 DNCIC2
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Protein Name:
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
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Background:
This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
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Function:
Function:The intermediate chains seem to help dynein bind to dynactin 150 kDa component.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Caution:Unlikely isoform. Several sequence problems.,similarity:Belongs to the dynein intermediate chain family.,similarity:Contains 7 WD repeats.,subunit:Consists of at least two heavy chains and a number of intermediate and light chains.,
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Cellular Localization:
Cytoplasm, cytoskeleton . Cytoplasm . Detected in the cytoplasm of pachytene spermatocytes. Localizes to the manchette in elongating spermatids. .
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Tissue Expression:
Research Areas:
>>Phagosome ;
>>Vasopressin-regulated water reabsorption ;
>>Salmonella infection
>>Vasopressin-regulated water reabsorption ;
>>Salmonella infection
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN0629
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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