Catalog: YN0578
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
CSPP1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
138kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
CSPP1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
138kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
CSPP1 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
CSPP1 CSPP
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Protein Name:
Centrosome and spindle pole-associated protein 1
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Background:
centrosome and spindle pole associated protein 1(CSPP1) Homo sapiens This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
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Function:
developmental stage:Expression of isoform 1 increases throughout the cell cycle and peaks in G2/M phase. Expression of isoform 2 is highest in G1 phase and decreases thereafter.,Function:May play a role in cell-cycle-dependent microtubule organization.,PTM:Phosphorylated. Phosphorylation increases in colcemide-treated cells.,subcellular location:Associated with mitotic spindles.,tissue specificity:Detected in testis.,
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Cellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole . Associated with mitotic spindles.
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Tissue Expression:
Expressed in adult and fetal brain with enrichment in the cerebellum. Detected in testis.
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Reference Citation({{totalcount}})
Catalog: YN0578
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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