Catalog: YN0091
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
MK04
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
64kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
MK04 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
64kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 410-490
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Specificity:
MK04 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
MAPK4 ERK4 PRKM4
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Protein Name:
Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK)
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Background:
Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Function:Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:High expression in heart and brain.,
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Cellular Localization:
Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
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Tissue Expression:
High expression in heart and brain.
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Research Areas:
>>IL-17 signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN0091
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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