Synthesized peptide derived from human CK15 AA range: 350-456

The antibody can specifically recognize human CK15 protein. In immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody specifically labels the squamous epithelial cells and carcinomas, and shows no reaction with glandular epithelial cells.

KRT15 KRTB

Cytokeratin-15

AI528832 ;
CK 15 ;
CK-15 ;
CK15 ;
CytokeRatin-15 ;
CytokeRatin15 ;
K15 ;
K1C15_HUMAN ;
K1CO ;
Ka15 ;
KeRatin 15 ;
KeRatin 15 basic ;
KeRatin 15 beta ;
KeRatin ;
KeRatin complex 1 acidic gene 15 ;
KeRatin type I cytoskeletal 15 ;
KeRatin-15 ;
KeRatin15 ;
KRT 15 ;
Krt1-15 ;
KRT15 ;
KRTB ;
KRTL15 ;
Type I cytoskeletal 15 ;
Type I keRatin Ka15

CK15 is a cytokeratin with a molecular weight of 50 kDa. It is mainly expressed in basal keratinocytes of stratified epithelium and is used for the diagnosis of squamous cell carcinoma.

miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,tissue specificity:Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.,

Cytoplasmic, Membranous

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