Catalog: YM3063
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
Kif 7
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
IHC, IF
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:50-200; IF 1:50-200
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
The antibody detects endogenous Kif 7 proteins.
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Modification
Unmodified
Clonality
Monoclonal
Clone Number
3F8
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Antigen&Target Information
Immunogen:
Synthetic Peptide of Kif 7
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Specificity:
The antibody detects endogenous Kif 7 proteins.
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Gene Name:
KIF7
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Protein Name:
Kinesin-like protein KIF7
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Other Name:
Kinesin-like protein KIF7
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Background:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],
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Function:
similarity:Belongs to the kinesin-like protein family. KIF27 subfamily.,similarity:Contains 1 kinesin-motor domain.,tissue specificity:Embryonic stem cells, melanotic melanoma and Jurkat T-cells.,
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Cellular Localization:
Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Localizes to the cilium tip.
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Tissue Expression:
Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.
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Research Areas:
>>Hedgehog signaling pathway ;
>>Pathways in cancer ;
>>Basal cell carcinoma
>>Pathways in cancer ;
>>Basal cell carcinoma
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM3063
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
Add to cart
Collected
Collect
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