Catalog: YM1032
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
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Collected
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Main Information
Target
eEF2
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB
MW
95kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-1:2000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
EF-2 Monoclonal Antibody detects endogenous levels of EF-2 protein.
Purification
Affinity purification
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
95kD
Modification
Unmodified
Clonality
Monoclonal
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RS0002
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Antigen&Target Information
Immunogen:
Purified recombinant human EF-2 protein fragments expressed in E.coli.
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Specificity:
EF-2 Monoclonal Antibody detects endogenous levels of EF-2 protein.
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Gene Name:
EEF2
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Protein Name:
Elongation factor 2
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Other Name:
EEF2 ;
EF2 ;
Elongation factor 2 ;
EF-2
EF2 ;
Elongation factor 2 ;
EF-2
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Database Link:
Background:
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008],
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Function:
Function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,
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Cellular Localization:
Cytoplasm . Nucleus . Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. .
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Tissue Expression:
Brain,Cajal-Retzius cell,Epithelium,Hepatocyte,Ovary,Periph
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Research Areas:
>>AMPK signaling pathway ;
>>Oxytocin signaling pathway
>>Oxytocin signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM1032
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
Collect
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