Catalog: YM0544
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
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Main Information
Target
Rab 10
Host Species
Mouse
Reactivity
Human, Mouse
Applications
WB, IF, ELISA
MW
23kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Rab 10 Monoclonal Antibody detects endogenous levels of Rab 10 protein.
Purification
Affinity purification
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
23kD
Modification
Unmodified
Clonality
Monoclonal
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Antigen&Target Information
Immunogen:
Purified recombinant fragment of human Rab 10 expressed in E. Coli.
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Specificity:
Rab 10 Monoclonal Antibody detects endogenous levels of Rab 10 protein.
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Gene Name:
RAB10
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Protein Name:
Ras-related protein Rab-10
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Other Name:
RAB10 ;
Ras-related protein Rab-10
Ras-related protein Rab-10
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Background:
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009],
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Function:
Function:May be involved in vesicular trafficking and neurotransmitter release.,similarity:Belongs to the small GTPase superfamily. Rab family.,
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Cellular Localization:
Cytoplasmic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane . Golgi apparatus, trans-Golgi network membrane . Endosome membrane . Recycling endosome membrane . Cytoplasmic vesicle, phagosome membrane . Cytoplasm, cytoskeleton, cilium basal body . Endoplasmic reticulum membrane . Cytoplasm, perinuclear region . Associates with SLC2A4/GLUT4 storage vesicles (PubMed:22908308). Localizes to the base of the cilium when phosphorylated by LRRK2 on Thr-73 (PubMed:20576682, PubMed:30398148). Transiently associates with phagosomes (By similarity). Localizes to the endoplasmic reticulum at domains of new tubule growth (PubMed:23263280). .
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Tissue Expression:
Expressed in the hippocampus (PubMed:29562525). Expressed in neutrophils (at protein level) (PubMed:29127255). Expressed in the testis (at protein level) (PubMed:28067790).
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Research Areas:
>>Endocytosis ;
>>AMPK signaling pathway
>>AMPK signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM0544
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
Collect
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