Catalog: YM0133
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
CD73
Host Species
Mouse
Reactivity
Human
Applications
IHC, IF, ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1:1000; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CD73 Monoclonal Antibody detects endogenous levels of CD73 protein.
Purification
Affinity purification
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Modification
Unmodified
Clonality
Monoclonal
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Antigen&Target Information
Immunogen:
Purified recombinant fragment of CD73 expressed in E. Coli.
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Specificity:
CD73 Monoclonal Antibody detects endogenous levels of CD73 protein.
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Gene Name:
NT5E
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Protein Name:
5'-nucleotidase
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Other Name:
NT5E ;
NT5 ;
NTE ;
5'-nucleotidase ;
5'-NT ;
Ecto-5'-nucleotidase ;
CD antigen CD73
NT5 ;
NTE ;
5'-nucleotidase ;
5'-NT ;
Ecto-5'-nucleotidase ;
CD antigen CD73
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Background:
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011],
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Function:
Catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,Disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,Function:Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,
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Cellular Localization:
Cell membrane ; Lipid-anchor, GPI-anchor .
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Tissue Expression:
Leukocyte,Liver,Placenta,Skin,
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Research Areas:
>>Purine metabolism ;
>>Pyrimidine metabolism ;
>>Nicotinate and nicotinamide metabolism ;
>>Metabolic pathways ;
>>Nucleotide metabolism
>>Pyrimidine metabolism ;
>>Nicotinate and nicotinamide metabolism ;
>>Metabolic pathways ;
>>Nucleotide metabolism
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Reference Citation({{totalcount}})
Catalog: YM0133
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
Collect
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