Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human,Mouse YY1 (Acetyl Lys351).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GEkPF
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
55kD
Modification
Acetyl
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human YY1 (Acetyl Lys351)
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Specificity:
This antibody detects endogenous levels of Human,Mouse YY1 (Acetyl Lys351).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GEkPF
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Gene Name:
YY1 INO80S
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Protein Name:
YY1 (Acetyl Lys351)
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Other Name:
Transcriptional repressor protein YY1 ;
Delta transcription factor ;
INO80 complex subunit S ;
NF-E1 ;
Yin and yang 1 ;
YY-1 ;
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008],
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Function:
Function:Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. May play an important role in development and differentiation. The function of YY1 as an activator or a repressor is specified by the presence of other proteins. For example it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence.,similarity:Belongs to the YY transcription factor family.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associated with the nuclear matrix.,subunit:Interacts with YAF2 through the region encompassing the first and second zinc fingers. Interacts with INO80.,
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Cellular Localization:
Nucleus matrix . Associated with the nuclear matrix.