Purified recombinant Human CD206

This recombinant monoclonal antibody can detects endogenous levels of CD206 protein.

MRC1 CLEC13D CLEC13DL MRC1L1

Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)

MRC1 ;
CLEC13D ;
CLEC13DL ;
MRC1L1 ;
Macrophage mannose receptor 1 ;
MMR ;
C-type lectin domain family 13 member D ;
C-type lectin domain family 13 member D-like ;
Macrophage mannose receptor 1-like protein 1 ;
CD206

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded byThis gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.,miscellaneous:CRDs 1-3 have at most very weak affinity for carbohydrate. CRD 4 shows the highest affinity binding and has multispecificity for a variety of monosaccharides. At least 3 CRDs (4, 5, and 7) are required for high affinity binding and endocytosis of multivalent glycoconjugates.,online information:Macrophage mannose receptor,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 ricin B-type lectin domain.,similarity:Contains 8 C-type lectin domains.,

Endosome membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein .

Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.