Purified recombinant Human CD27

This recombinant monoclonal antibody can detects endogenous levels of CD27 protein.

CD27 TNFRSF7

CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)

CD 27 antibody ;
CD27 antibody ;
CD27 antigen antibody ;
CD27 molecule antibody ;
CD27_HUMAN antibody ;
CD27L receptor antibody ;
LPFS2 antibody ;
MGC20393 antibody ;
OTTHUMP00000238557 antibody ;
S152 antibody ;
T cell activation antigen CD27 antibody ;
T cell antivation antigen S152 antibody ;
T-cell activation antigen CD27 antibody ;
T14 antibody ;
TNFRSF 7 antibody ;
TNFRSF7 antibody ;
TNFSF7 antibody ;
Tp 55 antibody ;
Tp55 antibody ;
Tumor necrosis factor receptor superfamily member 7 antibody ;
CD27 nanobody ;

CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]

Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Membrane; Single-pass type I membrane protein.

Detected on marginal zone and germinal center B cells in lymph nodes (PubMed:24631). Detected on blood B cells (at protein level) (PubMed:24631, PubMed:1667271).