Purified recombinant Human CD134

This recombinant monoclonal antibody can detects endogenous levels of CD134 protein.

TNFRSF4 TXGP1L

Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)

ACT 35 antibody ;
ACT35 antibody ;
ACT35 antigen antibody ;
ATC35 antigen antibody ;
CD 134 antibody ;
CD134 antibody ;
CD134 antigen antibody ;
IMD16 antibody ;
Lymphoid activation antigene ACT35 antibody ;
OX 40 antibody ;
OX40 antibody ;
OX40 antigen antibody ;
OX40 cell surface antigen antibody ;
OX40 homologue antibody ;
OX40L receptor antibody ;
TAX transcriptionally activated glycoprotein 1 receptor antibody ;
TAX transcriptionally-activated glycoprotein 1 receptor antibody ;
TNF receptor superfamily member 4 antibody ;
TNFRSF 4 antibody ;
TNFRSF4 antibody ;
TNR4_HUMAN antibody ;
Tumor necrosis factor receptor superfamily member 4 antibody ;
Txgp 1l antibody ;
Txgp1 antibody ;
Txgp1l antibody

CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.

Membrane; Single-pass type I membrane protein.

Detected on umbilical veil endothelial cells (PubMed:162579). Detected in placenta (at protein level) (PubMed:169283). Detected on endothelial cells (PubMed:169283).