Catalog: YF0110
Size
Price
Status
Qty.
10mg
$0.00
3 weeks
0
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Collected
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Main Information
Target
CD223
Host Species
Mouse
Reactivity
Human
Applications
FC, IF
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IF 1:200-1:1000; FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
Formulation
PBS, pH 7.4
Specificity
Endogenous
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5mg/ml
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTF0114
Isotype
Mouse IgG1/Kappa
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Antigen&Target Information
Specificity:
Endogenous
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Gene Name:
LAG3
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Protein Name:
Lymphocyte activation gene 3 protein
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Other Name:
LAG3 ;
FDC ;
Lymphocyte activation gene 3 protein ;
LAG-3 ;
Protein FDC ;
CD223
FDC ;
Lymphocyte activation gene 3 protein ;
LAG-3 ;
Protein FDC ;
CD223
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Database Link:
Background:
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008],
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Function:
Function:Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes.,
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Cellular Localization:
[Lymphocyte activation gene 3 protein]: Cell membrane ; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. .
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YF0110
Size
Price
Status
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10mg
$0.00
3 weeks
0
Add to cart
Collected
Collect
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