Synthesized peptide derived from human CREB5 AA range: 415-465

This antibody detects endogenous levels of CREB5 at Human/Mouse

CREB5 CREBPA

CREB5

The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Function:Binds to the cAMP response element and activates transcription.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.,

Nucleus .

>>cGMP-PKG signaling pathway ;
>>cAMP signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>AMPK signaling pathway ;
>>Longevity regulating pathway ;
>>Adrenergic signaling in cardiomyocytes ;
>>TNF signaling pathway ;
>>Thermogenesis ;
>>Cholinergic synapse ;
>>Dopaminergic synapse ;
>>Insulin secretion ;
>>Estrogen signaling pathway ;
>>Thyroid hormone synthesis ;
>>Glucagon signaling pathway ;
>>Aldosterone synthesis and secretion ;
>>Relaxin signaling pathway ;
>>Cortisol synthesis and secretion ;
>>Parathyroid hormone synthesis, secretion and action ;
>>Insulin resistance ;
>>Cushing syndrome ;
>>Growth hormone synthesis, secretion and action ;
>>Vasopressin-regulated water reabsorption ;
>>Huntington disease ;
>>Prion disease ;
>>Cocaine addiction ;
>>Amphetamine addiction ;
>>Alcoholism ;
>>Hepatitis B ;
>>Human cytomegalovirus infection ;
>>Human papillomavirus infection ;
>>Human T-cell leukemia virus 1 infection ;
>>Viral carcinogenesis ;
>>Chemical carcinogenesis - receptor activation ;
>>Prostate cancer