Catalog: YT5251
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
CD58
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, IF, ELISA
MW
27kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
27kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human CD58. AA range:31-80
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Specificity:
CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.
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Gene Name:
CD58
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Protein Name:
Lymphocyte function-associated antigen 3
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Other Name:
CD58 ;
LFA3 ;
Lymphocyte function-associated antigen 3 ;
Ag3 ;
Surface glycoprotein LFA-3 ;
CD58
LFA3 ;
Lymphocyte function-associated antigen 3 ;
Ag3 ;
Surface glycoprotein LFA-3 ;
CD58
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Background:
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],
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Function:
Function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,
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Cellular Localization:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.
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Tissue Expression:
Brain,Erythrocyte,
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Research Areas:
>>Cell adhesion molecules ;
>>Epstein-Barr virus infection
>>Epstein-Barr virus infection
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT5251
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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