The antiserum was produced against synthesized peptide derived from human PSMD6. AA range:201-250

p44S10 Polyclonal Antibody detects endogenous levels of p44S10 protein.

PSMD6

26S proteasome non-ATPase regulatory subunit 6

PSMD6 ;
KIAA0107 ;
PFAAP4 ;
26S proteasome non-ATPase regulatory subunit 6 ;
26S proteasome regulatory subunit RPN7 ;
26S proteasome regulatory subunit S10 ;
Breast cancer-associated protein SGA-113M ;
Phosphonoformate immuno-associated protein 4 ;

This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012],

Function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit S10 family.,similarity:Contains 1 PCI domain.,subunit:Component of the PA700 complex.,

proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle,proteasome accessory complex,extracellular exosome,

Bone marrow,Lymph,Mammary cancer,Ovary,Placenta,Testis,

>>Proteasome ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Spinocerebellar ataxia ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Epstein-Barr virus infection