Catalog: YT0414
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
ATPBD3
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, ELISA
MW
36kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
ATPBD3 Polyclonal Antibody detects endogenous levels of ATPBD3 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
36kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human ATPBD3. AA range:291-340
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Specificity:
ATPBD3 Polyclonal Antibody detects endogenous levels of ATPBD3 protein.
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Gene Name:
CTU1
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Protein Name:
Cytoplasmic tRNA 2-thiolation protein 1
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Other Name:
CTU1 ;
ATPBD3 ;
NCS6 ;
Cytoplasmic tRNA 2-thiolation protein 1 ;
ATP-binding domain-containing protein 3 ;
Cancer-associated gene protein ;
Cytoplasmic tRNA adenylyltransferase 1
ATPBD3 ;
NCS6 ;
Cytoplasmic tRNA 2-thiolation protein 1 ;
ATP-binding domain-containing protein 3 ;
Cancer-associated gene protein ;
Cytoplasmic tRNA adenylyltransferase 1
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Background:
function:Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,
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Function:
Function:Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,
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Cellular Localization:
Cytoplasm.
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Tissue Expression:
Brain,Epithelium,Teratocarcinoma,
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Research Areas:
>>Sulfur relay system
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT0414
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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