Catalog: YP1327
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
eIF4B
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
80kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human Mouse Rat eIF4B (phospho-Ser406)
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
80kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized phosho peptide around human eIF4B (Ser406)
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Specificity:
This antibody detects endogenous levels of Human Mouse Rat eIF4B (phospho-Ser406)
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Gene Name:
EIF4B
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Protein Name:
eIF4B (Ser406)
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Other Name:
Eukaryotic translation initiation factor 4B ;
eIF-4B ;
eIF-4B ;
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Function:
Function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,
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Cellular Localization:
cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
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Tissue Expression:
Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung
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Research Areas:
>>mTOR signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Proteoglycans in cancer
>>PI3K-Akt signaling pathway ;
>>Proteoglycans in cancer
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YP1327
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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