Catalog: YN3010
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
DLL4
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
75kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
DLL4 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
75kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
DLL4 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
DLL4 UNQ1895/PRO4341
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Protein Name:
Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4)
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Background:
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008],
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Function:
Domain:The Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.,Function:Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.,PTM:Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.,similarity:Contains 1 DSL domain.,similarity:Contains 8 EGF-like domains.,subunit:Binds to Notch-1 and Notch-4.,tissue specificity:Expressed in vascular endothelium.,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein .
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Tissue Expression:
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Research Areas:
>>Endocrine resistance ;
>>Notch signaling pathway ;
>>Th1 and Th2 cell differentiation ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - receptor activation ;
>>Breast cancer
>>Notch signaling pathway ;
>>Th1 and Th2 cell differentiation ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - receptor activation ;
>>Breast cancer
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN3010
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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