Catalog: YN2687
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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Main Information
Target
RXFP1
Host Species
Rabbit
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
MW
83kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
RXFP1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
83kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 240-320
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Specificity:
RXFP1 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
RXFP1 LGR7
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Protein Name:
Relaxin receptor 1 (Leucine-rich repeat-containing G-protein coupled receptor 7) (Relaxin family peptide receptor 1)
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Background:
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
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Function:
Function:Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein .
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Tissue Expression:
Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
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Research Areas:
>>Neuroactive ligand-receptor interaction ;
>>Relaxin signaling pathway
>>Relaxin signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN2687
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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