Synthesized peptide derived from human protein . at AA range: 140-220

BKRB2 Polyclonal Antibody detects endogenous levels of protein.

BDKRB2 BKR2

B2 bradykinin receptor (B2R) (BK-2 receptor)

This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008],

Function:Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Ubiquitous. Widespread in normal smooth muscle tissue and neurons.,

Cell membrane; Multi-pass membrane protein.

Ubiquitous. Widespread in normal smooth muscle tissue and neurons.

>>Calcium signaling pathway ;
>>cGMP-PKG signaling pathway ;
>>Sphingolipid signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Complement and coagulation cascades ;
>>Inflammatory mediator regulation of TRP channels ;
>>Regulation of actin cytoskeleton ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Chagas disease ;
>>Pathways in cancer