Catalog: YM9183
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
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Collected
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Main Information
Target
UBF-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
89kD (Calculated)
89kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:400-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
89kD
MW(Observed)
89kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT1341R
Isotype
IgG,Kappa
Related Products
Primary Antibodies
UBF-1 Rabbit pAb
YT4804
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Primary Antibodies
UBF-1 Rabbit pAb
YT4803
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Primary Antibodies
UBF-1 (Phospho Ser484) Rabbit pAb
YP0837
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ELISA Kits
Total UBF-1 Cell-Based Colorimetric ELISA Kit
KA3548C
More→
Antigen&Target Information
Specificity:
Endogenous
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Gene Name:
UBTF
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Protein Name:
Nucleolar transcription factor 1
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Other Name:
UBTF ;
UBF ;
UBF1 ;
Nucleolar transcription factor 1 ;
Autoantigen NOR-90 ;
Upstream-binding factor 1 ;
UBF-1
UBF ;
UBF1 ;
Nucleolar transcription factor 1 ;
Autoantigen NOR-90 ;
Upstream-binding factor 1 ;
UBF-1
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Background:
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011],
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Function:
Function:Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element.,PTM:Phosphorylated and activated by PIK3CA.,similarity:Contains 6 HMG box DNA-binding domains.,subunit:Homodimer. Binds to IRS1 and PIK3CA.,
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Cellular Localization:
Nucleus, nucleolus .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YM9183
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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