Catalog: YM8256
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
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Collected
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Main Information
Target
Msi1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
39kD (Calculated)
39kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:400; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Protein A
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
39kD
MW(Observed)
39kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT0953R
Isotype
IgG,Kappa
RRID
AB_3698843
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Antigen&Target Information
Specificity:
Endogenous
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Gene Name:
MSI1
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Protein Name:
RNA-binding protein Musashi homolog 1
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Other Name:
MSI1 ;
RNA-binding protein Musashi homolog 1 ;
Musashi-1
RNA-binding protein Musashi homolog 1 ;
Musashi-1
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Background:
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008],
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Function:
Domain:The first RNA recognition motif binds more strongly to RNA compared to the second one.,Function:RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.,similarity:Belongs to the Musashi family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.,
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Cellular Localization:
Cytoplasm . Nucleus .
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Tissue Expression:
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
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Research Areas:
>>mRNA surveillance pathway
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Reference Citation({{totalcount}})
Catalog: YM8256
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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