Catalog: YM3636
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
Ubiquitin
Host Species
Mouse
Reactivity
Human, Rat, Mouse, Pig
Applications
WB, IF, IHC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; IHC 1:100-200; IF 1:200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Ubiquitin protein detects endogenous levels of Ubiquitin
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Modification
Unmodified
Clonality
Monoclonal
Clone Number
5F1
RRID
AB_3717380
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RS0002
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Primary Antibodies
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Antigen&Target Information
Immunogen:
Synthetic Peptide of Ubiquitin
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Specificity:
Ubiquitin protein detects endogenous levels of Ubiquitin
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Protein Name:
Ubiquitin
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Background:
UBB (ubiquitin B) encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of UBB are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.
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Signaling Pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal
Cellular Processes >> Transport and catabolism >> Mitophagy - animal
Human Diseases >> Neurodegenerative disease >> Parkinson disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Genetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis
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Catalog: YM3636
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
Add to cart
Collected
Collect
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