Contact Us

408-747-0189
1-877-594-3616

Quick order

Cyclophilin B (2B10) Mouse mAb (HRP)

-YM2027

Main Information
Target

Cyclophilin B

Host Species

Mouse

Reactivity

Human, Rat, Mouse

Applications

IF, WB, IHC,

MW

24kD (Calculated)

Conjugate/Modification

HRP

Detailed Information
Recommended Dilution Ratio
Optimal working dilutions should be determined experimentally by the investigator; Suggested starting dilutions are as follows:WB 1:1000-2000; IHC 1:50-300.
Formulation
Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
Specificity
Cyclophilin B Monoclonal Antibody(2B10) HRP Conjugated, specially designed for your Western blot analysis.
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage
Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Concentration
1mg/ml
MW(Calculated)
24kD
Conjugate
HRP
Clonality
Monoclonal
Clone Number
2B10
Isotype
IgG
Related Products
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001

More→

Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002

More→

Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028

More→

Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029

More→

Antigen&Target Information
Specificity:
Cyclophilin B Monoclonal Antibody(2B10) HRP Conjugated, specially designed for your Western blot analysis.
show all
Gene Name:
PPIB
show all
Protein Name:
Peptidyl-prolyl cis-trans isomerase B (PPIase B) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)
show all
Other Name:
Cyclophilin B
show all
Database Link:
Organism Gene ID SwissProt
Human 5479; P23284;
Background:
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009],
show all
Function:
Catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,Caution:It is uncertain whether Met-1 or Met-9 is the initiator.,enzyme regulation:Cyclosporin A (CsA) inhibits CYPB.,Function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
show all
Cellular Localization:
Virion . (Microbial infection).; Endoplasmic reticulum lumen . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
show all
Tissue Expression:
Brain,Fetal brain cortex,Prostate,Skin,
show all

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}