The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
show all
Function:
Caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,Function:Molecular chaperone.,Function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,
show all
Cellular Localization:
Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.