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Catalog: YM1398
Size
Price
Status
Qty.
200μL
$450.00
3 weeks

0

100μL
$280.00
3 weeks

0

40μL
$160.00
3 weeks

0

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Collected

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Main Information
Target

HSP 90

Host Species

Mouse

Reactivity

Human, Mouse, Rat

Applications

WB

MW

90kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Hsp90 alpha and Hsp90 beta.
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Observed)
90kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
15C5
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Antigen&Target Information
Immunogen:
Purified recombinant human HSP90AA1 protein fragments expressed in E.coli
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Specificity:
This antibody detects endogenous levels of Hsp90 alpha and Hsp90 beta.
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Gene Name:
hsp90
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Other Name:
D6S182 ;
FLJ26984 ;
FLJ31884 ;
Heat shock 86 kDa ;
heat shock 90kDa protein 1 alpha ;
Heat shock protein 90kDa alpha cytosolic class A member 1 ;
Heat shock protein 90kDa alpha cytosolic class B member 1 ;
Heat shock protein HSP 90 alpha ;
Heat shock protein HSP 90 beta ;
Heat shock protein HSP 90-alpha ;
HS90A_HUMAN ;
HSP 84 ;
HSP 86 ;
Hsp 90 ;
HSP84 ;
HSP86 ;
Hsp89 ;
Hsp90 ;
HSP90 Beta ;
HSP90A ;
HSP90AA1 ;
HSP90AB1 ;
HSP90B ;
HSP90N ;
HSPC1 ;
HSPC2 ;
HSPCA ;
HSPCAL1 ;
HSPCAL4 ;
HSPCB ;
HSPN ;
LAP2 ;
Lipopolysaccharide associated protein2 ;
LPS associated protein 2 ;
NY REN 38 antigen ;
Renal carcinoma antigen NY-REN-38.
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Database Link:
Organism Gene ID SwissProt
Human 3320; P07900;
Mouse 15519; P07901;
Background:
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
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Function:
Caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,Function:Molecular chaperone.,Function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,
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Cellular Localization:
Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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Research Areas:
>>Protein processing in endoplasmic reticulum ;
>>PI3K-Akt signaling pathway ;
>>Necroptosis ;
>>Antigen processing and presentation ;
>>NOD-like receptor signaling pathway ;
>>IL-17 signaling pathway ;
>>Th17 cell differentiation ;
>>Progesterone-mediated oocyte maturation ;
>>Estrogen signaling pathway ;
>>Salmonella infection ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - receptor activation ;
>>Prostate cancer ;
>>Lipid and atherosclerosis ;
>>Fluid shear stress and atherosclerosis
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Catalog: YM1398
Size
Price
Status
Qty.
200μL
$450.00
3 weeks

0

100μL
$280.00
3 weeks

0

40μL
$160.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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