Catalog: YC0203
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
NOTCH3
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
75kD,260kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat NOTCH3 (Cleaved-Val1662, protein was cleaved amino acid sequence between 1661-1662 )
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
75kD,260kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human NOTCH3 (Cleaved-Val1662)
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Specificity:
This antibody detects endogenous levels of Human,Mouse,Rat NOTCH3 (Cleaved-Val1662, protein was cleaved amino acid sequence between 1661-1662 )
show all
Gene Name:
NOTCH3
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Protein Name:
NOTCH3 (Cleaved-Val1662)
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Other Name:
Neurogenic locus notch homolog protein 3 ;
Notch 3 ;
[Cleaved into: Notch 3 extracellular truncation ;
Notch 3 intracellular domain]
Notch 3 ;
[Cleaved into: Notch 3 extracellular truncation ;
Notch 3 intracellular domain]
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Database Link:
Cellular Localization:
Cell membrane ; Single-pass type I membrane protein.; [Notch 3 intracellular domain]: Nucleus. Following proteolytical processing NICD is translocated to the nucleus.
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Tissue Expression:
Research Areas:
>>Endocrine resistance ;
>>Notch signaling pathway ;
>>Apelin signaling pathway ;
>>Th1 and Th2 cell differentiation ;
>>Thyroid hormone signaling pathway ;
>>Human papillomavirus infection ;
>>Pathways in cancer ;
>>MicroRNAs in cancer ;
>>Breast cancer
>>Notch signaling pathway ;
>>Apelin signaling pathway ;
>>Th1 and Th2 cell differentiation ;
>>Thyroid hormone signaling pathway ;
>>Human papillomavirus infection ;
>>Pathways in cancer ;
>>MicroRNAs in cancer ;
>>Breast cancer
show all
Signaling Pathway
Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> MicroRNAs in cancer
Human Diseases >> Cancer: specific types >> Breast cancer
Environmental Information Processing >> Signal transduction >> Notch signaling pathway
Environmental Information Processing >> Signal transduction >> Apelin signaling pathway
Reference Citation({{totalcount}})
Catalog: YC0203
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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