Catalog: YA0623
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
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Collected
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Main Information
Target
CD19
Reactivity
Human
Applications
ELISA, FC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
ELISA 1:5000-100000
Formulation
Phosphate-buffered solution
Source
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Specificity
This recombinant monoclonal antibody can detects endogenous levels of CD19 protein.
Purification
Recombinant Expression and Affinity purified
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration
Please check the information on the tube
Modification
Unmodified
Clone Number
PN0405
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Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Antigen&Target Information
Immunogen:
Purified recombinant Human CD19
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Specificity:
This recombinant monoclonal antibody can detects endogenous levels of CD19 protein.
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Gene Name:
CD19
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Protein Name:
B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19)
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Other Name:
B-lymphocyte antigen CD19 ;
Cd19 ;
Differentiation antigen CD19 ;
CD19 ;
Antibody deficiency due to defect in CD19 antibody ;
Antibody deficiency due to defect in CD19 ;
included antibody ;
AW495831 antibody ;
B lymphocyte antigen CD19 antibody ;
B lymphocyte surface antigen B4 antibody ;
B-lymphocyte antigen CD19 antibody ;
B-lymphocyte surface antigen B4 antibody ;
B4 antibody ;
CD19 antibody ;
CD19 antigen antibody ;
CD19 molecule antibody ;
Cd19 protein antibody ;
CD19_HUMAN antibody ;
CVID3 antibody ;
Differentiation antigen CD19 antibody ;
Leu 12 antibody ;
Leu-12 antibody ;
Leu12 antibody ;
MGC109570 antibody ;
MGC12802 antibody ;
T-cell surface antigen Leu-12 antibody ;
Cd19 ;
Differentiation antigen CD19 ;
CD19 ;
Antibody deficiency due to defect in CD19 antibody ;
Antibody deficiency due to defect in CD19 ;
included antibody ;
AW495831 antibody ;
B lymphocyte antigen CD19 antibody ;
B lymphocyte surface antigen B4 antibody ;
B-lymphocyte antigen CD19 antibody ;
B-lymphocyte surface antigen B4 antibody ;
B4 antibody ;
CD19 antibody ;
CD19 antigen antibody ;
CD19 molecule antibody ;
Cd19 protein antibody ;
CD19_HUMAN antibody ;
CVID3 antibody ;
Differentiation antigen CD19 antibody ;
Leu 12 antibody ;
Leu-12 antibody ;
Leu12 antibody ;
MGC109570 antibody ;
MGC12802 antibody ;
T-cell surface antigen Leu-12 antibody ;
show all
Background:
CD19 molecule(CD19) Homo sapiens Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors.This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
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Function:
Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens . Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores . Is not required for early steps during B cell differentiation in the blood marrow . Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges . Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge .
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .
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Tissue Expression:
Blood,PCR rescued clones
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Signaling Pathway
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Organismal Systems >> Immune system >> T cell receptor signaling pathway
Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation
Organismal Systems >> Immune system >> Th17 cell differentiation
Organismal Systems >> Immune system >> IL-17 signaling pathway
Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway
Organismal Systems >> Immune system >> Intestinal immune network for IgA production
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Immune disease >> Asthma
Human Diseases >> Immune disease >> Autoimmune thyroid disease
Human Diseases >> Immune disease >> Inflammatory bowel disease
Human Diseases >> Immune disease >> Allograft rejection
Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
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Catalog: YA0623
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
Collect
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