Purified recombinant Human IL-5

This recombinant monoclonal antibody can detects endogenous levels of IL-5 protein.

IL5

Interleukin-5 (IL-5) (B-cell differentiation factor I) (Eosinophil differentiation factor) (T-cell replacing factor) (TRF)

IL5 ;
Interleukin-5 ;
IL-5 ;
B-cell differentiation factor I ;
Eosinophil differentiation factor ;
T-cell replacing factor ;
TRF ;
IL-5 nanobody ;

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production ofThis cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases.This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF).This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 .This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]

Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.,online information:Interleukin-5 entry,similarity:Belongs to the IL-5 family.,subunit:Homodimer; disulfide-linked.,

Secreted.

>>Proteasome ;
>>Cytokine-cytokine receptor interaction ;
>>HIF-1 signaling pathway ;
>>Necroptosis ;
>>TGF-beta signaling pathway ;
>>Osteoclast differentiation ;
>>Antigen processing and presentation ;
>>JAK-STAT signaling pathway ;
>>Natural killer cell mediated cytotoxicity ;
>>IL-17 signaling pathway ;
>>Th1 and Th2 cell differentiation ;
>>Th17 cell differentiation ;
>>T cell receptor signaling pathway ;
>>Type I diabetes mellitus ;
>>Leishmaniasis ;
>>Chagas disease ;
>>African trypanosomiasis ;
>>Malaria ;
>>Toxoplasmosis ;
>>Amoebiasis ;
>>Tuberculosis ;
>>Hepatitis C ;
>>Influenza A ;
>>Herpes simplex virus 1 infection ;
>>Pathways in cancer ;
>>PD-L1 expression and PD-1 checkpoint pathway in cancer ;
>>Inflammatory bowel disease ;
>>Systemic lupus erythematosus ;
>>Rheumatoid arthritis ;
>>Allograft rejection ;
>>Graft-versus-host disease ;
>>Fluid shear stress and atherosclerosis